Since 2013, SetUp Art Fair, has been held on the first floor of the Autostazione di Bologna located in Piazza XX Settembre 6, only 300 m from the Central Railway Station and in the heart of the city centre. The floor space of 2400 mq is divided into exhibiting space and facilities with conference rooms, press-­corner, lounge area, food & beverage point and reception with the offices.

The Bologna Autostazione centre is currently one of the most important points for passing travellers at European level with an annual throughput estimated at over 5 million passengers per year. The building, inaugurated in 1967 on the site of the former Littorio Youth Hostel , has housed important urban institutes and was the seat of public offices which gradually fell into disuse and were finally abandoned altogether.